Protein Purification Reagents and Kits
BIOHIPPO AAV-PTH-hChR2(H134R)-mCherry-WPRE-hGH-polyA
Recombinant adeno associated virus expressing hChR2(H134R) fused to mCherry under the PTH promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Abcam Ebselen, mimic of glutathione pero x idase, 25MG
MW 274.19 Da, Purity >98%. Seleno-organic compound, antioxidant, mimic of glutathione peroxidase. Inhibitor of lipoxygenases, NO synthases, NADPH oxidase, protein kinase C and H+/K(+)-ATPase producing anti-inflammatory effects.
The product is subject to the following: Abcam Restricted Use Statement
Genscript Corporation MSLN/Mesothelin298-600 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF)
Abcam TNB, Yellow chromogenic standard for DTNB thiol quantification, 1G
MW 199.19 Da, Purity =95%. TNB, Yellow chromogenic standard for DTNB thiol quantification. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen HES1 human rec His
Protein. Human HES1 aa 2-280 is fused at the N-terminus to a His-tag. Source E. coli. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >90% SDS-PAGE. bHLH proteins are essential for neurogenesis, myogenesis, hematopoiesis and sex determination. HES1 Hairy and Enhancer of Split 1 is a basic Helix-Loop-Helix bHLH transcriptional repressor regulated by the Notch pathway and expressed in various tissues. HES1 is well known in development of different tissues, particularly endoderm derived endocrine organs like pancreas and neuroendocrine cells of lung. HES1 controls normal development by regulating proliferation and differentiation and so cell fate. Notch signaling plays both oncogenic and tumor suppressor roles depending on cell type. In contrast to T cell acute lymphoblastic leukemia ALL, where Notch activation promotes leukemogenesis, induction of Notch signaling in B cell ALL B-ALL leads to growth arrest and apoptosis.
AdipoGen TAPBPL hFc hrec
Recombinant Protein. The extracellular domain of human TAPBPL aa 19-405 is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. T cells play critical roles in the adaptive immune system, protecting the human body against cancer, bacterial, viral, fungal and parasitic infections. T cell immune response is tightly controlled by immune checkpoint proteins that negatively or positively regulate T cell response. Among the immune checkpoint proteins, the B7 family plays a key role in controlling immune responses and belongs to the immunoglobulin Ig superfamily. A number of B7 family ligands have been identified, such as B7-1 CD80, B7-2 CD86, PD-L1 B7-H1, PD-L2 B7-DC, B7-H2 inducible T cell co-stimulator ligand ICOS, B7-H3, B7-H4 B7x, B7S1, B7-H5 VISTA and B7- H6. Because of the potential clinical applications of immune checkpoint proteins, there has been intense interest in identifying additional T-cell regulators.
Biotium Primary Antibody CD8a SK1 CF820 1/EA
CD8a (clone SK1) is a mouse monoclonal antibody that recognizes the human protein CD8 CD8a is a common marker of cytotoxic (Killer) T cells and is a T cell coreceptor This CF820 antibody conjugate has been validated in flow cytometry
Biotium CD45RA(111-1C5), Biotin conjugate, 0.1mg/mL
Recognizes a protein of 205 kDa-220 kDa, identified as CD45RA (Workshop III). CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4 T-cells, 50% of peripheral CD8 T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4 or CD8 T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO positive) from B cell lymphomas (CD45RA positive).Primary antibodies are available purified, or with a selection of fluoresc
AdipoGen Arginase I h highly active
Protein. Full length human arginase I. Source E. coli. Liquid. In 10mM TRIS-HCl, pH 7.5, containing 1mM beta-mercaptoethanol, 1mM MnCl2 and 50% glycerol. Purity >90% SDS-PAGE. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist types I and II which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Arginase is involved in the nitric oxide NO pathway and immune cell arginine metabolism. It is fundamentally involved in cancer, inflammation, infections, fibrotic diseases, neurobiology, pregnancy and immune regulation in general.
AdipoGen Arginase I h highly active
Protein. Full length human arginase I. Source E. coli. Liquid. In 10mM TRIS-HCl, pH 7.5, containing 1mM beta-mercaptoethanol, 1mM MnCl2 and 50% glycerol. Purity >90% SDS-PAGE. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist types I and II which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Arginase is involved in the nitric oxide NO pathway and immune cell arginine metabolism. It is fundamentally involved in cancer, inflammation, infections, fibrotic diseases, neurobiology, pregnancy and immune regulation in general.
AdipoGen NADK M tuberculosis His
Protein. NAD kinase Mycobacterium tuberculosis is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content N/A. Liquid. In 10mM TRIS at pH 8.0, containing 1mM MgCl2, 0.5mM EDTA, 1mM DTT and 1mM PMSF. Purity >98% SDS-PAGE. NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from Mycobacterium tuberculosis is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity ATP NAD = ADP NADP
AdipoGen CTRP5 human rec His
Protein. Human CTRP5 aa 16-243 is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Lyophilized from a 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >90% SDS-PAGE. CTRP5 C1qTNF-related protein 5 C1QTNF5 belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase AMPK in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration LORD.
AdipoGen FTO human rec His
Protein. Human FTO aa 2-505 is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >90% SDS-PAGE. FTO Fat mass-and obesity-associated gene is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
HARVARD BIOSCIENCE INC SLICE ANCHOR FOR RC-41-SS
Total order minimum requirement of $500 per supplier requirements. A $25.00 order fee will be applied if entire order is less than the $500 minimum requirement.